macula Play nounAn opaque spot on the cornea.nounThe macula lutea.nounA spot; a blotch.nounA spot, as on the skin, or on the surface of the sun or of some other luminous orb; called also macule.nounA rather large spot or blotch of color.nounAn oval yellow spot near the center of the retina of the human eye, histologically defined as having two or more layers of ganglion cells, responsible for detailed central vision.nounA spot, as on the skin, or on the surface of the sun or of some other luminous orb.nounA rather large spot or blotch of color.