verb

make (someone) worried or uneasy.

world leaders are surely disquieted by the prospect of a global economic meltdown

perturb,agitate,upset,disturb,unnerve,unsettle,discompose,disconcert,ruffle,startle,make uneasy,worry,make anxious,trouble,bother,concern,distress,alarm,appal,frighten,panic,make fretful,make restless,vex