profound

Having, showing, or requiring great insight or understanding.

Deeply felt or held; intense.

Thoroughgoing; far-reaching.

Unqualified or unbroken.

Situated at, extending to, or coming from a great depth; deep.

To cause to sink deeply; cause to penetrate far down.

To penetrate.

To dive; penetrate.

Deep; descending or being far below the surface, or far below the adjacent places; having great depth.

Specifically — In anatomy, deep-seated; not superficial: specifically applied to several structures, as arteries and muscles. See profunda.